MDMA can apparently be comedown-free, research says, producing an “afterglow” instead of a severe mood drop caused by a lack of serotonin.
Dr. Ben Sessa, a Bristol-based addictions psychiatrist, MDMA psychotherapist and psychedelic researcher, states that with medical MDMA use, there is no “post-dosing mood drop” making the well-known dreadful comedown “an artefact of sleep loss, excessive exercise and concomitant drug use.”
Earlier this year, Dr. Sessa published a research study that took place at the Imperial College London, where he began clinical trials for the treatment of alcoholism through the use of MDMA-assisted therapy. The researchers said they would use the study as a jumping-off point for further trials, and to devise additional studies using a placebo drug to see if the MDMA actually has an effect.
Check out Dr. Sessa's graphic below.
Best dosing recreationally:— Dr Ben Sessa MD (@DrSessa) September 22, 2019
T+2 hours: 60mg
T+4 hours: 30mg
T+6 hours: 15mg
T+8 hours: get cab home
Gives optimal positive mood effects & also safer; with reduced temp & BP risks.
People who understand MDMA know:
a) Never start >125mg
b) Halve dose every 2 hours