Set for release on February 3, the Jersey native's compilation marks his joining as one of Defected's House Masters, after more than three decades in the business.
Listeners can expect collaborations with renowned house vocalists including Inaya Day, Cece Rogers and Jocelyn Brown, plus powerful classics which propelled Romero to success including 'Night @ The Black' and 'Just Can't Get Enough'.
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It's been a busy time for Romero; he's recently worked with both Honey Dijon and Louie Vega, which reinforced Defected's decision to dub him "one of the most revered producers in the game" as he enters a new phase of his music curation.
'Defected presents House Masters - Harry Romero' is available to pre-order now. Do so here.
Niamh Ingram is Mixmag's Weekend Editor, follow her on Twitter